Collaborative Computational Project No. 4
Software for Macromolecular X-Ray Crystallography

APS Data collection workshop and CCP4 school: From data collection to structure refinement and beyond June 18 - June 26 2013

School Announcement

We are very pleased to announce the 6th annual CCP4 USA Crystallography School organized jointly with the National Institute of General Medical Sciences and National Cancer Institute Structural Biology Facility at the Advanced Photon Source (GM/CA@APS). The 2013 school will take place at the Advanced Photon Source (APS) synchrotron site at Argonne National Laboratory, near Chicago.

School Dates

June 18 - June 26, 2013
The first two days will be dedicated to data collection and processing. The rest of the school will focus on structure solution, refinement and validation.

School Details

Purpose of the course and intended audience

The course is intended mainly for graduate students, postdoctoral researchers and young scientists in the area of structural biology from all across the globe. The school is not meant as an introductory level course to protein crystallography. It is designed more for applicants with reasonable expertise in crystallography and experience with the CCP4 suite. The purpose of the school is to address specific problems that the applicants face while collecting diffraction data and while solving and refining novel structures. Applicants with crystals for data collection or with already collected data will be given strong consideration, although these are not mandatory requirements.

Several of the leading PX software developers from around the world will present lectures and tutorials on their software and will also be available to help with problems during hands-on sessions of the school.

Data Collection Workshop

The course will again be combined with a data collection workshop at the macromolecular crystallography beamlines 23ID-B and 23ID-D of the General Medicine and Cancer Institute Collaborative Access Team (GM/CA@APS) at the Advanced Photon Source (APS). This proved to be highly successful and popular with students of past workshops.

Participants will be encouraged to bring their crystals for data collection. However, the workshop beamtime cannot be used for crystal screening. Only samples with proven diffraction will be accepted. Limited screening may be allowed after all participants with well characterized crystals have completed data collection.

Some of the leading experts in the field will discuss strategies of data collection. GM/CA@APS staff will guide participants in beamline usage and will help during data collection.

Current capabilities of the beamlines, training courses and other details of GM/CA@APS can be found at

Data Processing and Structure Solution Workshop

The aim of this workshop will be to cover all aspects of the structure solution process in macromolecular crystallography, starting from data processing, through phasing and refinement, and ending with validation and deposition.

The workshop will cover many popular programs used for data processing and structure solution with the software developers available to help throughout the week. Programs covered will include: Mosflm, Scala, HKL2000, XDS, Refmac, ArpWarp, PHENIX, Phaser, Coot, SHELXC/D/E, Balbes, Mrbump, Buccaneer and many more.


There is no fee for the school. The students will be responsible for their transportation and lodging. If needed, the school organizers will help with making the reservations at the Argonne Guest House at a cost of about $70 per night. The school will also cover the expenses for all meals and refreshments.

Previous Schools

Links to the webpages for previous CCP4/APS schools.

2012 School

2011 School

2010 School

2009 School

2008 School