dear all,

Two 3-year postdoctoral positions (with possibility for extension) are available at Imperial College London to work on the mechanisms of human replication using biochemical and cryo-EM approaches. The application deadline is 19th of October 2021.

The Speck Lab works on initiation of eukaryotic DNA replication & the structure of chromatin + its regulation by epigenetic changes. We are looking for a passionate researchers with extensive expertise in Biochemistry (chromatin, DNA replication and related processes) and/or Structural Biology (extensive cryo-EM expertise is required).

Research framework and support structure:

1. The group consists of >10 members, 6 postdocs, 4 students and technician.
2. The lab is fully equipped for biochemistry (2 AKTAs, multiple temperature controlled shakers), two freezer mills, Refeyn 2, Biacore T100 and generously supported by the Wellcome Trust, Cancer Research UK and multiple BBSRC grants.
3. Access to state-of-the-art facilities including Mass Spectrometry, Structural Biology and Bioinformatics.
4. The candidate will receive direct mentoring by the group head on grant applications, writing of manuscripts and project design.
5. We have direct access to a local cryo-EM facility with a Talos 200KV FEG microscope and the LonCEM facility with a Krios (K3 & Falcon 3 detectors, phase plate, energy filter,..).
Interested individuals are welcome to contact me directly for more information.

Best,
Christian
chris.speck@imperial.ac.uk

here are a few links:

you can apply here:

Research Associate – Biochemistry & Structural Biology | Jobs | Imperial College London

The group:

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