A 2-year postdoctoral position (with possible extension) is available from the 1st of June 2022 in the team of Dr. Malene R. Jensen at the Institute for Structural Biology (IBS) in Grenoble, France. The successful candidate will work on the structure and dynamics of scaffold proteins and study their interactions with kinases of the mitogen-activated protein kinase (MAPK) cell signalling pathways. We exploit a combination of X-ray crystallography and NMR spectroscopy. 

More information can be found on the team website: www.jensen-nmr.fr

Facilities
The Institute for Structural Biology is located on the EPN science campus in Grenoble in close proximity to the European Synchrotron Radiation Facility (ESRF), the European Molecular Biology Laboratory (EMBL) Grenoble Outstation and the Institute Laue-Langevin (ILL). The IBS houses six high-field NMR spectrometers (3 x 600, 700, 850 and 950 MHz) and wetlab facilities for cloning, expression and purification of proteins. Access is facilitated to a number of state-of-the-art research platforms through Integrated Structural Biology Grenoble.

Qualifications
The ideal candidate holds a PhD in chemistry, biochemistry or biophysics (or related discipline) and has experience in protein expression and purification and a proven track-record in solution NMR spectroscopy and/or X-ray crystallography. To apply for this position, please send your CV, a motivation letter and the names of two referees to malene.ringkjobing-jensen@ibs.fr

K.K. Rasmussen, A. Palencia, A.K. Varming, H. El-Wali, E. Boeri Erba, M. Blackledge, K. Hammer, T. Herrmann, M. Kilstrup, L. Lo Leggio, M.R. Jensen

Proc. Natl. Acad. Sci. (2015) 112, 3409-3414.
Structure and dynamics of the MKK7-JNK signalling complex


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