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StartFragment
POSTDOCTORAL
POSITIONS
at Brown
University, USA
The
Deaconescu Lab at Brown University has two openings for postdoctoral researchers.
The laboratory’s interest is the interplay between DNA repair, transcription
and other cellular processes ensuring microbial adaptation to stressful
environments. We deploy a combination of biochemical, biophysical and structural
techniques. (e.g. X-ray crystallography, small-angle X-ray scattering,
transmission electron microscopy). For examples of work, please see Brugger et
al, Nature Communications (2021), Dorich et al., Genes and Development (2019), Le et al. Cell (2018), Vemu et al., Science (2018), Kutter et al. JMB (2016), Szyk et al, Cell (2014). Positions are partially or completely funded from NIH grants.
The first position is focused on
protein purification, characterization and structure determination by X-ray
crystallography. Previous experience with biophysical methods (ITC, MST, fluorescence)
and enzymatic assays a plus.
The second position will be focused on
cryo-EM. A successful candidate should be
familiar with specimen preparation, data collection as well as the processing
of images acquired using electron cryo-microscopy. We have our own Vitrobot for
specimen vitrification and access to state-of-the art electron microscopes at
Stanford/SLAC (remote data collection is possible) as well as a computing
cluster. If needed further training in EM can be provided.
The
candidates should also have the following qualifications: a Ph.D. in the field
of structural biology or related field; an established track-record of publications
in peer-reviewed journals. Must be
highly motivated and work independently as well as in a team. Excellent spoken
and written English are required. New Ph.D. graduates are encouraged to apply. The lab has its own Vitrobot, multiple protein
purification platforms and a crystallization robot etc. Access to EM facilities
also available.
Interested
candidates should send a CV, one page research experience summary and contact
information for three references to alexandra_deaconescu@brown.edu. Salary and starting date are negotiable. Please write Postdoctoral Candidate in the
e-mail subject header. Brown
University, an Ivy League school, is located less than one hour away by train
from Boston. Lab webpage:
https://deaconesculab.com
EndFragment
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