Postdoctoral
opportunity in Protein Design and Structural Biology

A postdoctoral position is available in the laboratory of Prof.
Filip Van Petegem at the University of British Columbia.  The goal is to apply state of the art
computational protein design methods to create novel protein molecules to
enable structural cryo-EM characterization of therapeutic candidates and their
target. The project is a collaboration with Amgen, one of the world’s
leading biotechnology companies, and is supported through a MITACS scholarship.

In recent years, antibody-based medicines have emerged as one of
the most effective modalities to treat diverse illnesses from cancer and
inflammation to metabolic and neurological disorders. The successful candidate
will work with experts in computational design to create novel scaffold
proteins and will gain hands-on experience in evaluating protein-protein
interactions in an industrial setting.

The
individual we seek has a background in computational protein design and an
interest in testing their designs in a laboratory setting.  We
are looking for a talented and highly motivated PhD graduate with a proven
track record in biochemistry, bioengineering, computer sciences or a related
discipline and a desire to push the envelope of biotherapeutic research.
Experience in protein structure visualization (i.e. PyMOL) and design tools
(i.e. Rosetta) is desired along with experience with protein purification and
experimental characterization. This position offers a unique opportunity in early-stage
drug discovery at the interface of academia and industry.

Please email your statement of interest and CV to:

Prof. Filip
Van Petegem

The
University of British Columbia

Filip.vanpetegem@gmail.com

Dr. Christy
A. Thomson

Amgen British
Columbia

cthomson@amgen.com

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