Dear all,

Could I draw your attention to a great position that we have available to join a two year, MRC DPFS-funded project to provide structural and biophysical input to a drug discovery project in the CRUK Newcastle Drug Discovery Unit.

The project is pursuing an exciting structural hypothesis to develop therapies to address an unmet need for treatments for patients with ovarian cancer.  It is currently in early lead optimisation, and the post holder will be joining a well founded
team to develop and apply techniques of structural biology (crystallography/cryo EM), biophysics (SPR/ITC), and cellular and cell-free assays to progress the project towards clinical candidate selection.

Because the work will be conducted in a group that has been instrumental in the development of licensed drugs, this post will offer the holder an insight into authentic and effective modern structure based drug discovery.  It would especially
suit someone looking to round off their structural biology skills with a view to pursuing careers in academic or industrial drug discovery.

Informal approaches can be made directly to myself (martin.noble@newcastle.ac.uk) or Jane Endicott (jane.endicott@newcastle.ac.uk),
but anyone considering the position should apply through the Newcastle University portal using the URL:

This link also offers further particulars for the post, for which the closing date is 22nd April.

With best wishes,

Martin

Martin
Noble

Professor
of Structural Biology and Anticancer
Drug Design

Translational
and Clinical Research Institute

Faculty
of Medical Sciences

Newcastle
University

Paul
O’Gorman Building

The
Medical School

Framlington
Place

Newcastle
Upon Tyne

NE2
4HH



Tel:
(+44) 191 2084466

E-mail:
martin.noble@ncl.ac.uk