——– Forwarded Message ——–

Subject:	Job opening for a post-doctoral research fellow in the cryo-EM facility of the European Synchrotron, ESRF, France
Date:	Fri, 3 Mar 2023 09:28:36 +0100
From:	Eaazhisai KANDIAH <eaazhisai.kandiah@esrf.fr>
Organization:	ESRF
To:	CCPEM@JISCMAIL.AC.UK

Dear Colleagues,

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I’d like to draw your
attention to a job opening for a post-doctoral
research fellow in the cryo-EM facility of the European
Synchrotron, ESRF, France

CM01 is the ESRF’s cryo-EM
facility dedicated to performing high-resolution imaging
of biological macromolecules, particularly for the
structural analysis of large, difficult to crystallize,
protein-protein or protein-nucleic acid complexes. CM01
has been designed to complement, and create synergy with,
the existing ESRF macromolecular crystallography and
BioSAXS beamlines and it is operated as a joint effort
from the four institutes (ESRF, EMBL, IBS and ILL) located
on the EPN campus. CM01 is equipped with a Krios G3
microscope and state-of-the-art K3 direct electron
detector and a GATAN LS Quantum energy filter. CM01 offers
single particle analysis (SPA) to users worldwide, and in
the near future cryo-electron tomography (cryo-ET) as
well. For more details on CM01, click here.

The postdoctoral position
available will focus on the method development in areas
important for CM01 notably in SPA data analysis and
cryo-ET. As for all postdoctoral researchers in the
Structural Biology Group, the successful candidate will
contribute to the operation of CM01 and will provide
support to external users as local contact. Furthermore,
the selected candidate will also participate in a research
program aimed at the structural characterization of the
non-structural proteins of coronavirus and in particular
of SARS-CoV2. The research project focuses on the
molecular mechanisms of three non-structural proteins in
viral replication by employing an integrative structural
biology approach, including cryo-ET and SPA.

For direct inquiries, please
contact Eaazhisai Kandiah (eaazhisai.kandiah@esrf.fr).

Expected profile

• PhD
  in biophysics, biology or closely related science
  obtained less than 3 years ago
• A
  strong background in cryo-EM
• A
  strong interest in method development for cryo-EM
• Background
  in structural biology and protein production is
  desirable
• Knowledge
  of membrane proteins is an asset
• Ability
  to interact with multi-disciplinary staff and facility
  users
• Proficiency
  in English (working language at the ESRF)

More information on the working
conditions and the application portal are found here.

Kindly please forward this email
to relevant colleagues who might be interested. Thanks
very much!

Best wishes

Isai