PhD project: Drug discovery at the interface of DEL screening,
cryo EM and AI machine learning

A 4-year fully-funded PhD position is available in Wyatt Yue’s lab at Newcastle
University, under the MoSMed CDT
programme at Newcastle and Durham (UK).

The project builds on the lab’s track record in structural studies of human metabolic enzymes, to discover chemical starting points for inhibitor design, through
working closely with medicinal (Mike Waring) and computational (Daniel Cole)
chemists at the university, as well as an AI drug discovery company (Standigm
Inc).

The student will receive training in protein biophysics and
cryo-EM (Yue), and have hands-on experience in DNA-encoded library screening
(Waring), protein-ligand simulations (Cole), and machine learning compound
design (Standigm).

Details of the project as well as instructions on how to
apply can be found here: NBDTP
(ncl.ac.uk)

The studentship is open to UK/EU/international applicants,
with deadline on 23:59 GMT Wednesday 2^nd March.

Enquiries on the project can be emailed to wyatt.yue@newcastle.ac.uk