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Dear all,
we are seeking a computational scientist to integrate the
multidimensional scaling program, PaSiMap, and its underlying
cc_analysis pipeline (references below) into the sequence alignment
viewer Jalview. This integration will advance the flexibility of PaSiMap
in testing suitable identity matrix for the best clustering of sequence
sets. The work is within the context of an existing collaboration
between the laboratories of Prof Kay Diederichs, Prof Olga Mayans and Dr
Jennifer Fleming at the University of Konstanz.
For this post, Java experience is essential. Background in biological
informatics is desirable, but not a pre-requisite.
The position is available at 50% for 4 months (July-October). Because of
the limited hiring period, the position is better suited to candidates
already located in our geographical area. Candidates must have completed
a Master degree in a suitable discipline and have demonstrated
capabilities in this area.
Applications must be in the form of a CV, degree transcripts and a
short letter describing existing expertise.
Applications and informal enquiries are to be directed to:
Jennifer.Fleming@uni-konstanz.de
Best Regards,
Jennifer Fleming
—–
http://pasimap.biologie.uni-konstanz.de
Su K, Mayans O, Diederichs K and Fleming JR (2022) PaSiMap: Pairwise
sequence similarity mapping with PaSiMap: reclassification of
immunoglobulin domains from titin as case study. Computational and
Structural Biotechnology Journal.
PaSiMap/ cc_analysis applications:
Zacharchenko T, Dorendorf T, Locker N, van Dijk E, Katzemich A,
Diederichs K, Bullard B, Mayans O. (2023). PK1 from Drosophila obscurin
is an inactive pseudokinase with scaffolding properties. Open Biology.
2023 Apr;13(4):220350. doi: 10.1098/rsob.220350.
Hunkler S, Diederichs K, Kukharenko O, Peter C. Fast conformational
clustering of extensive molecular dynamics simulation data. J Chem Phys.
2023 Apr 14;158(14):144109. doi: 10.1063/5.0142797.
—
Dr Jennifer Fleming
DFG Investigator
Fachbereich Biologie
Universität Konstanz
78457 Konstanz
Germany
Email: jennifer.fleming@uni-konstanz.de
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