The Yue Lab, recently relocated to Newcastle, is
recruiting 3 postdoc positions offering exciting opportunities in different flavours of structural
biology/drug discovery, interacting closely with clinicians, industry, and patient groups.

All are two-year positions in the first instance,
UK/EU/non-EU/international applicants all welcome.

Deadline: Monday 13 December. We aim to fill these
positions by Q1 2022.

 

https://jobs.ncl.ac.uk/job/Newcastle-Research-Associate/711931801/
(job ID: 11461) You will drive a structure-based drug discovery project in an
academic setting, funded by LifeArc and Action Medical Research, working
closely with medicinal chemists in Oxford and clinical scientists in UCL
towards hit-to-lead inhibitor optimisation for a rare epileptic disorder.
(Skills: crystallography, SPR, activity assays, CETSA; bit of cryo-EM)

https://jobs.ncl.ac.uk/job/Newcastle-Research-Associate-in-Structure-Based-Drug-Design/711711601/
(job ID: 11462) You will run an academic-industrial collaboration with Bicycle
Therapeutics, towards structural and biophysical characterisation of bicyclic
peptides in complex with novel therapeutic targets in
immune-metabolism/oncology. (Skills: different expression approaches,
crystallography, SPR; bit of cryo-EM)

https://jobs.ncl.ac.uk/job/Newcastle-Research-AssistantAssociate-in-AI-&-fragment-based-drug-discovery/743752301/
(job ID: 13927) You will lead an early-stage discovery project funded by a
patient foundation, towards small molecule therapy for Friedreich’s ataxia
targeting a multi-protein complex. You will work closely with an AI company in
hit finding, and run validation studies to guide compound design through machine
learning (Skills: ITC, SPR, cryo-EM & x-ray, activity assays).

 

You can find out more about our group here: https://www.staff.ncl.ac.uk/yuelab/

Any informal enquiries you can contact: wyatt.yue@newcastle.ac.uk

 

 

Wyatt Yue

Professor of Structural Biology

Biosciences Institute

Faculty of Medical Sciences

Newcastle University NE2 4HH

Group: www.staff.ncl.ac.uk/yuelab/

Profile: wyattyue.github.io