Dear Colleagues,
The Christianson group at the University of Pennsylvania is hiring postdoctoral fellows who are interested in studying structure-function relationships in histone deacetylases (HDAC’s) and terpene biosynthetic enzymes. Our work with HDAC’s currently focuses on inhibitor design and development in collaboration with other academic labs as well as the pharmaceutical industry; our work in terpene biosynthesis currently focuses on bifunctional terpene synthases and mechanisms of tandem catalysis. Experience with protein crystallography and/or cryo-EM is required. Links to examples of recent work are below. If interested, please send a brief note of interest and a c.v. to chris@sas.upenn.edu.
https://www.nature.com/articles/s41467-025-60537-3
https://www.nature.com/articles/s41467-026-73146-5
https://www.pnas.org/doi/10.1073/pnas.2408064121
Many thanks,
David Christianson
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David W. Christianson, Ph.D.
Roy and Diana Vagelos Professor in
Chemistry and Chemical Biology
University of Pennsylvania
231 South 34th Street
Philadelphia, PA 19104-6323 USA
(215) 898-5714