Duke University is hiring a protein core director position. Please pass this opportunity along those who might be interested. Thanks. 

Duke University School of Medicine

Departments
of Biochemistry and Cell Biology

Protein Core Director

 

The Director
of the Protein Design and Analysis Core provides visionary scientific and
operational leadership for a multidisciplinary core facility dedicated to the
de novo design, engineering, characterization, and structural analysis of
proteins. The Director oversees a team of scientists, engineers, and technical
staff, and serves as a strategic partner to internal research programs and
external collaborators. This role demands expertise at the intersection of
computational protein design, structural biology, and biophysical
characterization, combined with the management acumen to operate a
high-throughput, service-oriented research core.

 

Qualified
candidates will have a Ph.D. in Biochemistry, Structural Biology,
Biophysics, Computational Biology, Bioengineering, or a closely related field
with a minimum of 8–10 years of post-doctoral research or industry experience,
with at least 3–5 years in a leadership or supervisory role.

 

Demonstrated
deep expertise in protein expression systems (bacterial, mammalian, insect),
purification, and quality control is essential as well as a strong command of
biophysical characterization techniques (SPR, ITC, SEC-MALS, CD, DLS, HDX-MS). Proficiency
in structural biology methods (X-ray crystallography and/or cryo-EM) and
associated software pipelines is required, with hands-on experience with
computational protein design platforms (Rosetta, AlphaFold, ESMFold, or
equivalent) and relevant scripting languages (Python, PyMOL scripting, etc.).

 

Highly
qualified candidates will have a proven track record of scientific productivity
evidenced by peer-reviewed publications in high-impact journals, with demonstrated
ability to manage complex, multi-stakeholder projects and lead
interdisciplinary teams.

 

All applications should be
submitted through: Research Scholar Job Details | Duke Careers

 

Duke University is an Equal
Opportunity Employer. Please note that Duke will specifically seek information
about past misconduct or policy violations (in the past ten (10) years) and/or
relevant pending investigations as part of the application process. Disclosures
will not be an automatic bar to hiring but, instead, will initiate further
dialogue regarding past actions and steps taken to address them. Disclosures
will not be shared with search committees during the application review
process.

 

Important Dates: Review of applications will begin September 20^th,
2026.