A postdoctoral position is available immediately
in the Pazgier Laboratory at the Uniformed Services University of the
Health Sciences (USU) in Bethesda, MD. We are seeking a highly motivated
and skilled postdoctoral fellow with expertise in both immunology
and structural biology to participate in an interdisciplinary research
program focused on structural immunology using X-Ray crystallography/Cryo-EM
and Cryo-ET.

Research Focus

The successful candidate will contribute to ongoing projects
aimed at elucidating Fc-effector mechanisms of the adaptive immune response
(including IgG and IgA) to HIV-1 with the ultimate goal of identify
effective strategies to preserve immune function and promote healthy aging.
Projects will leverage high-resolution structural methods to dissect the
interactions between antibodies, viral proteins, and Fc receptors, and will
integrate structural data with functional immunological assays.

Required Qualifications

• A
  Ph.D. in immunology, structural biology, biochemistry, molecular
  biology, or a closely related field.
• Demonstrated
  expertise in X-Ray-crystallography,
  Cryo-Electron Microscopy (Cryo-EM) and/or Cryo-Electron
  Tomography (Cryo-ET) for structural determination.
• Solid
  understanding of human immune response, particularly B cell
  responses, antibodies, Fc receptors, and antigen-antibody interactions.
• Strong
  technical skills in molecular cloning, protein expression and
  purification, and molecular interaction analysis (e.g., SPR,
  BLI).
• A
  strong track record of peer-reviewed publications.
• Excellent
  interpersonal, organizational, and communication skills (oral and
  written).
• A
  collaborative, team-oriented mindset and enthusiasm for interdisciplinary
  research.

Preferred Qualifications

• Experience
  with hybrid approaches that integrate Cryo-EM/cryo-ET with X-ray
  crystallography, computational modeling
• Experience
  in antibody engineering or Fc-effector function assays
  (ADCC, ADCP).
• Familiarity
  with immune repertoire analysis, epitope mapping, or systems
  serology approaches.

Why Join Us?

USU is located directly across from the NIH campus in
Bethesda, placing it in the heart of one of the most vibrant biomedical
research communities in the world. Our lab benefits from access to outstanding core
facilities, including those for Next-Generation Sequencing, Cryo-EM,
Bioinformatics, and High-Performance Computing. USU offers a strongly
collaborative environment, with weekly Immunology data clubs, journal
clubs, and frequent research seminars featuring both local and
international speakers.

We welcome applicants at all career stages who are excited
to work in a multidisciplinary and translational environment.

To apply please respond to marzena.pazgier@usuhs.edu