A postdoctoral position is available
in the Kory lab at the Harvard T.H.
Chan School of Public Health to investigate the biochemical mechanisms of
mitochondrial metabolite transport.

 

We are looking for highly motivated individuals with a
background in in vitro biochemistry, structural biology and/or biophysics to
join our multi-disciplinary international team. The strong focus on molecular
and mechanistic research in metabolism, and age-related diseases in the Department of Molecular Metabolism and the general excellence of biomedical research in the area
provide an ideal environment for postdoctoral training with relevance to human
health and disease.

https://www.hsph.harvard.edu/molecular-metabolism/

 

Research in the Kory lab focuses on the role of organelles
in metabolic compartmentalization and regulation. Our current work centers on
mitochondria, critical organelles in metabolism generating both energy and precursors for biosynthesis.
Beyond their metabolic roles, mitochondria are being recognized as important
signaling hubs and mitochondrial dysfunction has been associated with major
diseases including cancer, diabetes, and neurodegeneration. 

The Kory lab takes multi-faceted approaches including
biochemistry, structural biology, functional genomics, metabolite profiling,
imaging and mouse models to determine how mitochondria achieve efficient
metabolite exchange and conversion while maintaining the unique chemical
environment of the mitochondrial matrix. Ultimately, we hope our research in
understanding mitochondrial metabolite transport in humans will contribute to
progress in the treatment of diseases with deregulated metabolism such as cancer
and diabetes.

 

For more information, please visit: https://kory-lab.com/

The ideal candidate has a strong background in in vitro
biochemistry, structure biology and/or biophysics and experience in methods and
technologies such as protein expression and purification, thermostability
assays, in vitro reconstitution, activity and binding assays, methods for
protein structure determination, cross-linking mass spectrometry, and will join
ongoing efforts in developing and applying systematic approaches to transporter
identification and characterization.

Please contact Dr. Nora Kory (nkory@hsph.harvard.edu) with your CV, a cover outlining your past research experience and your motivation for joining the lab, as well as contact information for 2-3 references.

Qualifications:

Basic Qualifications 

• Ph.D. in biochemistry, biological sciences, biophysics, or a related field
• Motivation to understand metabolite transport, biology and disease at a mechanistic
• Excellent communication, writing, and organizational skills
• In-depth biochemistry/structural biology/biophysics experience

AdditionallQualifications  AdditionallQualificationslorlExpertiselinlanyloflthelfollowinglareaslislvalued: • Metabolomics, proteomics, mass spectrometry • Microfluidics • Microscopy