A
NIH-funded postdoctoral research position is open in the laboratory of Dr.
Seok-Yong Lee at Duke University School of Medicine. The successful candidate
will have the opportunity to explore the molecular-level mechanisms of the
machinery that underpin membrane transport processes that are critical to human
health.

The
Lee Lab’s research is currently centered around three main areas of membrane
transport: calcium permeation in somatosensation, drug/metabolite transport,
and polysaccharide transport in microbial cell wall synthesis. The types of
questions we ask are: what is the molecular basis of temperature and irritant
sensing and why is mint cooling and wasabi spicy? How do fungi and bacteria
construct their intricate cell walls, and how can these mechanisms be targeted
by drugs? How are nutrients and drugs taken up into cells, and how can we
improve drug specificity and potency? To probe these questions the lab employs
a diverse range of techniques, including cryo-electron microscopy (cryo-EM),
biochemistry, biophysics, chemical biology, and computational approaches.

Recent notable publications from the lab include:

• Yin
  et al., Science, 2022
• Wright,
  Fedor, et al., Nature, 2022
• Ren
  et al., Nat. Struct. & Mol. Biol., 2022
• Kwon
  et al., Nat. Commun., 2022
• Kwon
  et al., Nat. Struct. & Mol. Biol., 2021

For more information, visit the Lee Lab website: https://sites.duke.edu/leelab/

This
position presents an exceptional opportunity for skilled biochemists or
structural biologists with an interest in connecting structural biology to
membrane biology. Candidates will benefit from joining a diverse and highly
collaborative research group with excellent training opportunities and research
facilities. A strong background in either cryo-EM or membrane protein
biochemistry is advantageous, but not mandatory.

To apply, please submit the following materials to seok-yong.lee@duke.edu:

• Curriculum
  vitae or resume including a list of publications and contact information
  for three references
• Statement
  of research interests

Durham, home to Duke University, is consistently ranked as
one of the best places to live in the United States with lush countryside and
driving distance to the Atlantic Ocean and Appalachian Mountains. For more
information on the city, consult the recent U.S. News and World Report rating: https://realestate.usnews.com/real-estate/slideshows/25-best-places-to-live-in-the-us