Hello,

At Schrödinger (https://www.schrodinger.com/), we are seeking outstanding and highly motivated scientists to work on structure-based drug discovery in our new labs in Natick, MA, just outside of Boston (https://xtalbiostructures.com/).

If you are interested in i) joining a cross-functional group of scientists and drug developers with experience working on all common target classes and therapeutic areas, ii) using breakthrough computational methods, and iii) contributing to our rapidly expanding portfolio of drug discovery programs and collaborations, please apply following the links provided below.

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Principal Scientist/Lab Head – Protein Sciences
https://boards.greenhouse.io/schrdinger/jobs/4924812003?gh_src=cd0d760c3us.

Key responsibilities:
Implement and oversee gene-to-protein capabilities for structural biology applications.
Establish, perform, and oversee experimental protocols and tasks in the areas of molecular biology (gene construct design), protein expression (using mammalian, insect, bacterial cell systems), and protein purification.

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Senior Scientist – Protein Biochemistry and Biophysics / Structural Biology
https://boards.greenhouse.io/schrdinger/jobs/4924506003?gh_src=839a2b363us

Key responsibilities:
Contribute to construct design and expression of proteins in multiple host species (E. coli, insect, mammalian).
Perform protein purification for structural biology applications (X-ray crystallography and cryo-EM).
Perform protein characterization using biophysical methods (ITC, SPR, TSA, etc.).
Perform protein crystallization and grid preparation for X-ray crystallography and cryo-EM.

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Scientist – Protein Production Specialist
https://boards.greenhouse.io/schrdinger/jobs/4924817003?gh_src=13238cf73us

Key responsibilities:
Work on a gene-to-protein pipeline for structural biology applications.
Perform experimental procedures in the areas of molecular biology (gene construct design) and protein expression using different cell systems (mammalian, insect, bacterial).

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Best regards,

Enrico Malito
Executive Director, Structural Biology
Schrödinger, NY, USA

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