Hi All,

We have an exciting job opportunity in structural biology!  Please apply at:

H3 is an oncology-focused company leveraging the
latest cancer genomics data to inform drug discovery.  The qualified candidate will have a Ph.D. and
postdoc with 2-4 years of relevant industry experience.  They will be responsible for leading
structure based drug design efforts using x-ray crystallography and cryo-EM
methods, as required.  The candidate will
also manage CRO relationships and possible academic collaborations.

Basic qualifications:

Molecular Biology (construct design)

Expression (from E coli, insect &
mammalian systems) and purification (AKTA)

Automation (Mosquito, DragonFly,
RockMaker, etc)

Co-crystallization, seeding,
cross-seeding, soaking, harvesting, freezing, etc. 

Molecular Replacement, CCP4, Coot,
Pymol or Chimera, Heavy atom of Se-Met phasing

Grid preparation & freezing

Relion, cisTEM, CCP-EM, etc

Two or more first author
publications.  

Team player and excellent
communication skills

Additional desired qualifications:

Knowledge
of drug discovery & oncology. 
Experience in biophysics. 
Experience with cryo-EM.

—

Nick Larsen

Director – Lead Discovery
H3 Biomedicine | an Eisai Oncology Company
300 Technology Sq #5
Cambridge, MA 02139
Mobile: 617-792-4184

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