Category: Scientific
Job ID: R-102328
Location: Burnaby, BC, CA
Additional Location:
Posted Date: 7/29/2020

Title: Senior Scientist – Protein Technologies Team Lead

Reports to: Principal Scientist

Location: Burnaby


Amgen is a global biotechnology company that discovers and develops
breakthrough therapies to treat serious human illnesses. Our mission is to
serve patients around the world and our medicines have made a dramatic
difference in the lives of millions.

Amgen focuses on areas of high unmet medical need and leverages its
expertise to strive for solutions that improve health outcomes and
dramatically improve people’s lives. A biotechnology pioneer since 1980,
Amgen has grown to be one of the world’s leading independent biotechnology
companies, has reached millions of patients around the world and is
developing a pipeline of medicines with breakaway potential.

Amgen’s Therapeutic Discovery organization is seeking an enthusiastic,
collaborative Senior Scientist team lead to join the Protein Technologies
group at our Amgen British Columbia site. Protein Technologies is
responsible for designing, planning and executing on the generation of key
enabling DNA and protein reagents to support discovery of small and large
molecule therapeutics and cutting-edge novel modalities.

As a team lead within Protein Technologies, you will be responsible for
managing a high-performing team with a mandate to produce high quality
reagents to support the Amgen pipeline. You will be responsible for the
operational, strategic, and scientific management of the group and will
also actively participate in the science through hands-on lab work and
implementation of enabling technologies and automation. You will also be
responsible for aligning with our Protein Technologies group in South San
Francisco and for initiating and driving collaborations with partner
functions such as such as Antibody Discovery, Therapeutic Areas, and
Molecular Structure.

Well-suited applicants will have a strong scientific background in
recombinant protein expression, purification, and analytics, a deep
scientific curiosity, and demonstrated success in project and personnel

Basic Qualifications

Doctorate degree and 3 years of Scientific experience
Master’s degree and 6 years of Scientific experience
Bachelor’s degree and 8 years of Scientific experience

Preferred Qualifications

– Ph.D. in Biochemistry, Biophysics, Chemistry or Molecular Biology and
postdoc from a leading institution or biotechnology company
– 4+ years of industry experience
– A track record of scientific accomplishments and project leadership in
biologics drug development as evidenced by peer-reviewed publications,
patents, or pipeline contributions
– 2+ years of managing a high-performing team with a focus on protein
expression, purification, and analytics
– Expertise in recombinant protein expression in transient and stable
mammalian hosts such as HEK293 and CHO
– Expertise in purifying a range of different protein types (e.g.
extracellular domains, glycoproteins, monoclonal and multi-specific
antibodies, membrane proteins) using multiple chromatographic methods (e.g.
affinity, ion exchange, size exclusion)
– Expertise in protein analytics, including HPLC-SEC and LC-MS
– Experience with increasing productivity through automation
– Microbial protein expression experience
– Familiarity with processes in antibody discovery
– Strong written and verbal communication and interpersonal skills
– Ability to inspire and grow a high-performing team, chart and set team
goals into action, and forge productive cross-site collaborations with
partner functions

Amgen endeavors to make its recruitment process accessible to any and all
users. Reasonable accommodations will be provided, upon request, to
applicants with disabilities in order to facilitate equal opportunity
throughout the recruitment and selection process. Please contact to make a request and ensure you
include the requisition number.

Reasonable accommodations are available, upon request, to facilitate the
equal participation of candidates with disabilities, should you be selected
for an interview*.*

Join Us

If you’re seeking a career where you can truly make a difference in the
lives of others, a career where you can work at the absolute forefront of
biotechnology with the top minds in the field, you’ll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative
human therapeutics. Our medicines have helped millions of patients in the
fight against cancer, kidney disease, rheumatoid arthritis and other
serious illnesses.

As an organization dedicated to improving the quality of life for people
around the world, Amgen fosters an inclusive environment of diverse,
ethical, committed and highly accomplished people who respect each other
but compete intensely to win. Together, we live the Amgen values as we
continue advancing science to serve patients.