Dear all,

we have an open position for a post-doctoral researcher to join the Klaholz group at the Centre for Integrative Biology, IGBMC, Illkirch, France http://igbmc.fr/Klaholz

We are studying the structure and function of large nucleoprotein complexes (ribosome complexes, chromatin complexes, viruses) through integrated structural biology, including biochemistry, crystallography, high resolution cryo-EM, tomography, super-resolution imaging & software developments.

We are looking for a highly motivated scientist with relevant expertise in structural biology, ideally with strong expertise in cryo electron microscopy. For further details please see below.

2 further positions are available on our structural biology platform http://frisbi.eu/centers/instruct-center-france-1-igbmc/:

With best regards,

Bruno Klaholz

For ongoing projects and full publication list of the team see http://igbmc.fr/Klaholz

Our group is located at the Centre for Integrative Biology (CBI) at IGBMC, Illkirch/Strasbourg, France, which comprises cutting-edge cryo-EM facilities:

The CBI provides a state-of-the-art scientific and technological environment in integrated structural biology to address the structure and function of biological systems, notably on gene expression, from the atomic, molecular to the tissue scales. The CBI http://www.igbmc.fr/grandesstructures/cbi/ hosts the French and European Infrastructures for Integrated Structural Biology, FRISBI http://frisbi.eu/, Instruct-ERIC https://www.structuralbiology.eu/ and iNext-Discovery https://inext-discovery.eu/network/inext-d/home which comprises advanced electron microscopy facilities equipped with cutting-edge instrumentation such as cryo electron microscopes including a Titan Krios, a Glacios (under installation), a Polara, cryo Focused Ion Beam Scanning Electron Microscope (cryo-FIB/SEM) and super-resolution fluorescence microscopy, see http://frisbi.eu/centers/instruct-center-france-1-igbmc/cryo-electron-microscopy/. The Titan Krios microscope is equipped with K3 camera, Falcon 3 camera, GIF energy filter and phase plate. In addition, the EM facility has a suite of associated equipments for sample preparation and dedicated computing resources for image processing and 3D reconstruction by single particle cryo-EM and cryo electron tomography.

Highly-motivated candidates with a recent PhD or MD/PhD in structural biology and specifically in cryo-EM are encouraged to apply.

Candidates should have strong expertise in protein biochemistry, in cryo-ET and/or in cryo-EM, image processing & atomic model refinement with various programs; computational skills are a strong plus. The candidate should have excellent writing and communication skills in English, be able to work independently and have a strong team spirit.

We are studying the structure and function of protein complexes (ribosome complexes, chromatin complexes, viruses) through integrated structural biology, including biochemical and biophysical methods, crystallography, high resolution cryo-EM, tomography, super-resolution imaging & software developments. Several projects are available for outstanding young scientists who would like to combine these approaches.

Applications should be sent via email to klaholz@igbmc.fr including CV, list of publications, names of 3 referees and motivation letter. The postdoctoral position remains open until filled.

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Bruno P. Klaholz
Centre for Integrative Biology
Department of Integrated Structural Biology
Institute of Genetics and of Molecular and Cellular Biology
IGBMC – UMR 7104 – U 1258
1, rue Laurent Fries
BP 10142
67404 ILLKIRCH CEDEX
FRANCE
Tel. from abroad: 0033.369.48.52.78
Tel. inside France: 03.69.48.52.78
websites:
http://www.igbmc.fr/research/department/3/team/36/
http://www.igbmc.fr/grandesstructures/cbi/
http://frisbi.eu/
http://instruct-eric.eu/
https://inext-discovery.eu/