A Postdoctoral Research Associate position is available in the laboratory of Dr. Doryen Bubeck at Imperial College London starting Jan. 2021. The post is funded for 3 years by a European Research Council Consolidator Grant. The main objective of the post is to use structural biology to characterise the 3D structure and mode of action of complement protein complexes in model membranes, building off our recently published structures of the complement membrane attack complex (Serna et al., 2016 Nature Communications https://www.nature.com/articles/ncomms10587; Menny et al., 2018 Nature Communications https://www.nature.com/articles/s41467-018-07653-5).
Complement plays an important role in innate immunity; however uncontrolled activation can damage human cells. Broadly, the goal of this project is to understand how cells protect themselves from damage during an immune response. This post provides an exciting opportunity to work as a key member of an interdisciplinary structural biology project that has the potential to impact complement therapeutics.
The posts will be based at the South Kensington Campus of Imperial College London, in the Department of Life Sciences. The Imperial College Centre for Structural Biology is a state-of-the-art electron microscopy facility with regular access to Titan Krios facilities at eBIC (Diamond Light Source) and the London Consortium for cryoEM (LonCEM).
For more information about the post and to apply online please visit
Informal enquires can be made directly to Dr. Doryen Bubeck (dbubeck at imperial.ac.uk).
Our preferred method of application is online via this website. Please download the application form and save to your computer. Please then upload a research CV and a covering letter in addition to a completed application form and apply via the website.
Closing date: 27th Aug. 2020