DLS-CCP4 Data Collection and Structure Solution Workshop

This page lists some of the publications where the research involved benefited from the assistance given at the DLS-CCP4 workshop. We are grateful to each of the authors for acknowledging the help they received at the workshop.

• 2023 Workshop
• 2021 Workshop
• 2019 Workshop
• 2018 Workshop
• 2017 Workshop
• 2016 Workshop
• 2015 Workshop
• 2014 Workshop

2023 Workshop

• Kedari, Ashwini, Liina Hannula, Rupesh Balaji Jayachandran, and Ilona Rissanen. ‘Structural Landscape of Engineered Multivalent Antibody Fragments and Their Application as Crystallization Scaffolds’. Preprint, 29 October 2024. https://doi.org/10.1101/2024.10.29.620886.
• Yapici, Ilkin, and Hasan Demirci. ‘Temperature-Dependent Structural Dynamics of SOD1 Revealed by Serial Synchrotron Crystallography’. Abant Medical Journal 14, no. 3 (2025): 208–24. https://doi.org/10.47493/abantmedj.1817591.
• Yapici, Ilkin, Arda Gorkem Tokur, Belgin Sever, Halilibrahim Ciftci, Ayse Nazli Basak, and Hasan DeMirci. ‘Structural Insights into the Dynamics of Water in SOD1 Catalysis and Drug Interactions’. International Journal of Molecular Sciences 26, no. 9 (2025): 4228. https://doi.org/10.3390/ijms26094228.

2021 Workshop

• Fernandes, Andreia, Adele Williamson, Pedro M. Matias, and Elin Moe. 2023. ‘Structure/Function Studies of the NAD+-Dependent DNA Ligase from the Poly-Extremophile Deinococcus Radiodurans Reveal Importance of the BRCT Domain for DNA Binding’. Extremophiles 27 (3): 26. https://doi.org/10.1007/s00792-023-01309-z.
• Guneri, Dilek, Effrosyni Alexandrou, Kamel El Omari, et al. ‘Structural Insights into I-Motif DNA Structures in Sequences from the Insulin-Linked Polymorphic Region’. Nature Communications 15, no. 1 (2024): 7119. https://doi.org/10.1038/s41467-024-50553-0.

2019 Workshop

• Smirnov, Igor, Natalia Kolganova, Romualdo Troisi, Filomena Sica, and Edward Timofeev. 2021. ‘Expanding the Recognition Interface of the Thrombin-Binding Aptamer HD1 through Modification of Residues T3 and T12’. Molecular Therapy - Nucleic Acids 23 (March): 863–71. https://doi.org/10.1016/j.omtn.2021.01.004.
• Orlans, Julien, Carole Vincent-Monegat, Isabelle Rahioui, Catherine Sivignon, Agata Butryn, Laurent Soulère, Anna Zaidman-Remy, et al. 2021. ‘PGRP-LB: An Inside View into the Mechanism of the Amidase Reaction’. International Journal of Molecular Sciences 22 (9): 4957. https://doi.org/10.3390/ijms22094957.

2018 Workshop

• De Benedetti, Stefano, Flavio Di Pisa, Enrico Mario Alessandro Fassi, Marina Cretich, Angelo Musicò, Roberto Frigerio, Alessandro Mussida, et al. ‘Structure, Immunoreactivity, and In Silico Epitope Determination of SmSPI S. Mansoni Serpin for Immunodiagnostic Application’. Vaccines 9, no. 4 (1 April 2021): 322. https://doi.org/10.3390/vaccines9040322.
• Butt, Benjamin G, Danielle J Owen, Cy M Jeffries, Lyudmila Ivanova, Chris H Hill, Jack W Houghton, Md Firoz Ahmed, et al. 2020. ‘Insights into Herpesvirus Assembly from the Structure of the PUL7:PUL51 Complex’. ELife 9 (May): e53789. https://doi.org/10.7554/eLife.53789.

2017 Workshop

• Linnert, Miriam, Claudia Fritz, Christian Jäger, Dagmar Schlenzig, Daniel Ramsbeck, Martin Kleinschmidt, Michael Wermann, Hans-Ulrich Demuth, Christoph Parthier, and Stephan Schilling. 2021. ‘Structure and Dynamics of Meprin β in Complex with a Hydroxamate-Based Inhibitor’. International Journal of Molecular Sciences 22 (11): 5651. https://doi.org/10.3390/ijms22115651.
• Sponga, Antonio, Joan L. Arolas, Thomas C. Schwarz, Cy M. Jeffries, Ariadna Rodriguez Chamorro, Julius Kostan, Andrea Ghisleni, et al. 2021. ‘Order from Disorder in the Sarcomere: FATZ Forms a Fuzzy but Tight Complex and Phase-Separated Condensates with α-Actinin’. Science Advances 7 (22): eabg7653. https://doi.org/10.1126/sciadv.abg7653.
• Fernandes, Humberto, Honorata Czapinska, Katarzyna Grudziaz, Janusz M. Bujnicki, and Martyna Nowacka. 2018. ‘Crystal Structure of Human Acinus RNA Recognition Motif Domain’. PeerJ 6 (July): e5163. https://doi.org/10.7717/peerj.5163.
• Czapinska, Honorata, Wojciech Siwek, Roman H. Szczepanowski, Janusz M. Bujnicki, Matthias Bochtler, and Krzysztof J. Skowronek. 2019. ‘Crystal Structure and Directed Evolution of Specificity of NlaIV Restriction Endonuclease’. Journal of Molecular Biology 431 (11): 2082–94. https://doi.org/10.1016/j.jmb.2019.04.010.
• Meijer, Femke A., Richard G. Doveston, Rens M.J.M. de Vries, Gaël M. Vos, Alex A.A. Vos, Seppe Leysen, Marcel Scheepstra, Christian Ottmann, Lech-Gustav Milroy, and Luc Brunsveld. 2020. ‘Ligand-Based Design of Allosteric Retinoic Acid Receptor-Related Orphan Receptor Γt (RORγt) Inverse Agonists’. Journal of Medicinal Chemistry 63 (1): 241–59. https://doi.org/10.1021/acs.jmedchem.9b01372.
• Vries, Rens M. J. M., Richard G. Doveston, Femke A. Meijer, and Luc Brunsveld. 2020. ‘Elucidation of an Allosteric Mode of Action for a Thienopyrazole RORγt Inverse Agonist’. ChemMedChem 15 (7): 561–65. https://doi.org/10.1002/cmdc.202000044.
• Vries, Rens M. J. M. de, Femke A. Meijer, Richard G. Doveston, Iris A. Leijten-van de Gevel, and Luc Brunsveld. 2021. ‘Cooperativity between the Orthosteric and Allosteric Ligand Binding Sites of RORγt’. Proceedings of the National Academy of Sciences 118 (6). https://doi.org/10.1073/pnas.2021287118.

2016 Workshop

• Kotila, Tommi, Konstantin Kogan, Giray Enkavi, Siyang Guo, Ilpo Vattulainen, Bruce L. Goode, and Pekka Lappalainen. 2018. ‘Structural Basis of Actin Monomer Re-Charging by Cyclase-Associated Protein’. Nature Communications 9 (1): 1892. https://doi.org/10.1038/s41467-018-04231-7.
• Koliopoulos, Marios G., Mathilde Lethier, Annemarthe G. van der Veen, Kevin Haubrich, Janosch Hennig, Eva Kowalinski, Rebecca V. Stevens, et al. 2018. ‘Molecular Mechanism of Influenza A NS1-Mediated TRIM25 Recognition and Inhibition’. Nature Communications 9 (1): 1820. https://doi.org/10.1038/s41467-018-04214-8.

2015 Workshop

• Vielberg, Marie-Theres, Verena C. Bauer, and Michael Groll. 2018. ‘On the Trails of the Proteasome Fold: Structural and Functional Analysis of the Ancestral β-Subunit Protein Anbu’. Journal of Molecular Biology 430 (5): 628–40. https://doi.org/10.1016/j.jmb.2018.01.004.
• Lobner, Elisabeth, Anne-Sophie Humm, Kathrin Göritzer, Georg Mlynek, Martin G. Puchinger, Christoph Hasenhindl, Florian Rüker, Michael W. Traxlmayr, Kristina Djinović-Carugo, and Christian Obinger. 2017. ‘Fcab-HER2 Interaction: A Ménage à Trois. Lessons from X-Ray and Solution Studies’. Structure 25 (6): 878-889.e5. https://doi.org/10.1016/j.str.2017.04.014.
• Jackson, Verity A., Shahid Mehmood, Matthieu Chavent, Pietro Roversi, Maria Carrasquero, Daniel del Toro, Goenuel Seyit-Bremer, et al. 2016. ‘Super-Complexes of Adhesion GPCRs and Neural Guidance Receptors’. Nature Communications 7 (1): 11184. https://doi.org/10.1038/ncomms11184.
• Bebel, Aleksandra, Ezgi Karaca, Banushree Kumar, W Marshall Stark, and Orsolya Barabas. 2016. ‘Structural Snapshots of Xer Recombination Reveal Activation by Synaptic Complex Remodeling and DNA Bending’. ELife 5 (December): e19706. https://doi.org/10.7554/eLife.19706.

2014 Workshop

• Marie, Léa, Chiara Rapisarda, Violette Morales, Mathieu Bergé, Thomas Perry, Anne-Lise Soulet, Clémence Gruget, Han Remaut, Rémi Fronzes, and Patrice Polard. 2017. ‘Bacterial RadA Is a DnaB-Type Helicase Interacting with RecA to Promote Bidirectional D-Loop Extension’. Nature Communications 8 (1): 15638. https://doi.org/10.1038/ncomms15638.
• Russo Krauss, Irene, Sneha Ramaswamy, Stephen Neidle, Shozeb Haider, and Gary N. Parkinson. 2016. ‘Structural Insights into the Quadruplex–Duplex 3′ Interface Formed from a Telomeric Repeat: A Potential Molecular Target’. Journal of the American Chemical Society 138 (4): 1226–33. https://doi.org/10.1021/jacs.5b10492.