Collaborative Computational Project No. 4
Software for Macromolecular X-Ray Crystallography

SSRF

CCP4 School: Structure Solution in Macromolecular X-Ray Crystallography
Mar 28th - Mar 31st 2011

Speakers

The following speakers will be present at the school (more to be added when confirmed):

Professor Hai-fu Fan   OASIS  Institute of Physics, Chinese Academy of Sciences, Beijing
Dr. Garib Murshudov   Refmac, BALBES  York Structural Biology Laboratory, York University, UK
Dr. Raj Pannu   CRANK, home page  Universiteit Leiden, Nederland
Dr. Bernhard Lohkamp   home page  Karolinska Institute, Stockhom, Sweden
Dr. Judit Debreczeni    Astra Zeneca, UK
Dr. Paul Emsley  Coot, home page  University of Oxford, UK
Dr. Melanie Vollmar   SGC  Structural Genomics Consortium, Oxford, UK
Dr. Martyn Winn   CCP4, home page  STFC Daresbury Lab, UK

Program

Basic Daily Schedule

Morning Breakfast
Lectures on theoretical background of software package(s)
Afternoon Lunch
Tutorials on software package(s) discussed in the morning
Evening Dinner
Problem solving sessions

Detailed Program

The following program is still subject to change. A printable version (pdf format) of the program will be available later.

28 March 2011
Data Processing and Molecular ReplacementInstructorLocation
8:00
Breakfast
9:00WelcomeTBCRoom 116
9:10Introduction to the courseMartyn Winn
9:30Data processing: Mosflm and iMosflmJudit Debreczeni
10:30
Coffee
11:00Scaling: Scala and PointlessJudit Debreczeni
11:45Introduction to MR, Dimple and MrBUMPMartyn Winn
12:30
Lunch
2:00 Tutorial 1: MosflmJudit + othersRoom 121
3:30
Coffee
4:00 Tutorial 2: Scala, DimpleJudit, Martyn + others
6:00
Dinner
7:00-10:00 Problem solving for volunteersAll
 
29 March 2011
Molecular Replacement and Experimental PhasingInstructorLocation
8:00
Breakfast
9:00BalbesGarib MurshudovRoom 116
9:45MR case studiesMelanie Vollmar
10:30
Coffee
11:00Automatic experimental phasing with CrankRaj Pannu
11:45OASIS, dual-space phasing and model completionHai-fu Fan
12:30
Lunch
2:00 Tutorial 1: MR with Balbes, MrBUMPGarib, Martyn + othersRoom 121
3:30
Coffee
4:00 Tutorial 2: OASISHai-fu Fan + others
6:00
Dinner
7:00-10:00 Problem solving for volunteersAll
 
30 March 2011
Building and RefinementInstructorLocation
8:00
Breakfast
9:00Introduction to phase improvement and model buildingRaj PannuRoom 116
9:45Introduction to Coot, including model building toolsBernhard Lohkamp
10:30
Coffee
11:00Autobuilding in BuccaneerPaul Emsley
11:45RefmacGarib
12:30
Lunch
2:00 Tutorial 1: CrankRaj + othersRoom 121
3:30
Coffee
4:00 Tutorial 2: Coot and BuccaneerBernhard, Paul + others
6:00
Dinner
7:00-10:00 Problem solving for volunteersAll
 
31 March 2011
Ligands and validationInstructorLocation
8:00
Breakfast
9:00Sketcher, Jligand, ProdrgGarib MurshudovRoom 116
9:45Ligand tools in CootPaul/Judit
10:30
Coffee
11:00Validation in CootBernhard
11:45Proofreading of structures in SGCMelanie Vollmar
12:30
Lunch
2:00 Tutorial 1: RefinementGarib + othersRoom 121
3:30
Coffee
4:00 Tutorial 2: LigandsGarib, Paul + others
6:00
Dinner
7:00-10:00 Problem solving for volunteersAll
 

Supported by: BBSRC CCP4 Biophysical Society of China SI Institute of Biophysics Chinese Crystallographic Society Hong Kong