[ccp4bb]: MARIE CURIE RESEARCH FELLOWSHIPS

["Demetres D. Leonidas" <ddl@eie.gr>]

***  For details on how to be removed from this list visit the  ***
***          CCP4 home page http://www.ccp4.ac.uk         ***


*MARIE CURIE RESEARCH FELLOWSHIPS*

Applications are invited for research training positions under a 
Marie-Curie Fellowships for Early Stage Research Training project with 
the title: "A European Research Training Site for the Design and 
Synthesis of Novel Neuroprotective and Hypoglycaemic Agents through a 
Multi-disciplinary approach" (EURODESY). For further information please 
visit the *EURODESY* 
<http://www.eie.gr/nhrf/institutes/iopc/eu-projects/eurodesy/vacancies-en.html> 
site.

This project will be implemented at the _Institute of Organic and 
Pharmaceutical Chemistry (IOPC)_ 
<http://www.eie.gr/nhrf/institutes/iopc/index-en.html> of the National 
Hellenic Research Foundation (NHRF) <http://www.eie.gr> of Athens, Greece

To be eligible, the applicants must fulfil the criteria for Marie-Curie 
Fellows

/NHRF is an equal opportunity employer./

The following positions will be available from February 2006.  
Reimbursement will be at the standard rates for Marie Curie Fellows.

*Position 1*

We seek to recruit a chemistry graduate, with not more than 4 years of 
research experience at post-graduate or equivalent level who will be 
trained in the synthesis of series of antioxidants, combining in one 
molecular scaffold structural features responsible for the radical 
scavenging as hydroxy stilbenoid dendrimers and iron chelators. 
Familiarity with organic synthetic methodologies, methods of 
purification and identification (NMR, GC, GC-MS, FT-IR) will be 
considered an asset. The duration of the fellowship will be 18 months.

Applications should be e-mailed to mskreta@eie.gr 
<mailto:mskreta@eie.gr>  and should include a full CV, and the names and 
addresses of 2-3 referees.

*Position 2*

We seek to recruit a chemistry graduate, with not more than 4 years of 
research experience at post-graduate or equivalent level who will be 
trained in organic synthesis, and in particular in synthetic pathways 
for the preparation of glucopyranosyl-modified thiosemicarbazones, 
potential inhibitors of GP. This fellow will also determine the kinetic 
constants of GP inhibitors using in vitro assays. Familiarity with 
organic synthetic methodologies, methods of purification and 
identification (NMR, GC, GC-MS, FT-IR) will be considered an asset.The 
applicant should hold a B.Sc. or an M.Sc degree in chemistry.The 
duration of the fellowship will be 34 months and may lead to PhD.

Applications should be e-mailed to Dr I.D. Kostas ( ikostas@eie.gr 
<mailto:ikostas@eie.gr> ) and should include a full CV, and the names 
and addresses of 1-2 referees. 

*Position 3*

We seek to recruit a chemistry graduate, with not more than 4 years of 
research experience at post-graduate or equivalent level who will be 
trained in the application of high-energy ultrasound and microwave 
techniques in organic and organometallic synthesis. Familiarity with 
organic synthetic methodologies, methods of purification and 
identification (NMR, GC, GC-MS, FT-IR) will be considered an asset. The 
duration of the fellowship will be 18 months.

Applications should be e-mailed to Dr. G. Heropoulos ( gherop@eie.gr 
<mailto:gherop@eie.gr> ) and should include a full CV, and the names and 
addresses of 2-3 referees.

*Position 4*

The Structural and Chemical Biology Group is seeking to recruit a Ph.D. 
student with not more than 4 years of research experience at 
post-graduate or equivalent level. The applicant should hold a B.Sc. or 
an M.Sc degree in chemistry, biology, biochemistry or another related 
discipline. The duration of the fellowship will be 36 months.

The fellow will focus his/her research on structural studies of 
inhibitors in complex with glycogen phosphorylase (GP) and the truncated 
form of the g-subunit of phosphorylase kinase (PhKÎ trn). His/her 
project will involve purification of GP and PhKgtrunc; crystallization, 
X-ray data collection, structure determination, refinement and analysis 
of GP- and PhKÎ trn-inhibitor complexes; determination and analysis of 
enzyme kinetic parameters for the designed and synthesized inhibitors. 
Training will be provided for this fellow with the latest methodologies 
of X-ray structural biology, protein expression and purification and 
biochemical characterization. This training will eventually lead to a 
Ph.D. thesis.

Applications should be e-mailed to Dr. N.G. Oikonomakos ( ngo@eie.gr 
<mailto:ngo@eie.gr> ) or Dr. D.D. Leonidas ( ddl@eie.gr 
<mailto:ddl@eie.gr> ) and should include a full CV, and the names and 
addresses of 2 referees.

*Position 5*

We seek to recruit a Ph.D. student with not more than 4 years of 
research experience at post-graduate or equivalent level. The applicant 
should hold a B.Sc. or an M.Sc degree in chemistry, biology, 
biochemistry or another related discipline. The position will be 
available from February 2006. The duration of the fellowship will be 36 
months. The fellow will focus his/her research on applications of ab- 
initio and semi-empirical calculations as well as of NMR spectroscopy to 
study the conformational analysis of novel synthetic bioactive compounds 
and on applications of biophysical techniques to study drug:membrane 
interactions.

Applications should be e-mailed to Dr. T. Mavromoustakos ( tmavro@eie.gr 
<mailto:tmavro@eie.gr> ) or Dr. M. Papadopoulos ( mpapad@eie.gr 
<mailto:mpapad@eie.gr> ) and should include a full CV, and the names and 
addresses of 2 referees.

--
Demetres D. Leonidas, Ph.D.
Structural & Chemical Biology Group
Institute of Organic and Pharmaceutical Chemistry
The National Hellenic Research Foundation
48, Vassileos Constantinou Avenue
Athens 116 35, Greece
==================================================
Tel. +30 210 7273841 (office)
    +30 210 7273895 (lab) 
Fax. +30 210 7273831
E-mail: ddl@eie.gr
URL: http://athena.eie.gr/~demetres
==================================================