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[ccp4bb] Postdoctoral position in biochemistry/structural biology at Harvard Medical School



Postdoctoral position in biochemistry/structural biology at Harvard Medical School
 
A postdoctoral position is available for cryo-EM analysis of the core protein complexes of the mammalian circadian clock, a molecular oscillator present in all or nearly all cells that drives daily rhythms of physiology and behavior.  Applicants should be scientifically ambitious, have a Ph.D. (or equivalent), and be accomplished in structural biology and/or the biochemical study of protein complexes.  Expertise in cryo-EM would be especially desirable.  We have made progress in single-particle analysis of native circadian clock complexes purified from mouse tissues (Aryal et al., Mol. Cell, 67, 770-782 [2017]).  Our early studies provide the first structural glimpse of native circadian clock machinery from a eukaryote, and we aim to obtain high-resolution structures.  Our long-term goal is to understand the mammalian circadian clock oscillator in terms of the actions of its handful of macromolecular machines.
 
Please send a cover letter, curriculum vitae, and the names, telephone numbers, and email addresses of three references to Charles J. Weitz, M.D., Ph.D.   Email:  cweitz@hms.harvard.edu