Postdoctoral position in biochemistry/structural biology at Harvard Medical School
A postdoctoral position is available for cryo-EM analysis of the core protein complexes of the mammalian circadian clock, a molecular oscillator present in all or nearly all cells that drives daily rhythms of physiology and behavior. Applicants should be scientifically ambitious, have a Ph.D. (or equivalent), and be accomplished in structural biology and/or the biochemical study of protein complexes. Expertise in cryo-EM would be especially desirable. We have made progress in single-particle analysis of native circadian clock complexes purified from mouse tissues (Aryal et al., Mol. Cell, 67, 770-782 ). Our early studies provide the first structural glimpse of native circadian clock machinery from a eukaryote, and we aim to obtain high-resolution structures. Our long-term goal is to understand the mammalian circadian clock oscillator in terms of the actions of its handful of macromolecular machines.
Please send a cover letter, curriculum vitae, and the names, telephone numbers, and email addresses of three references to Charles J. Weitz, M.D., Ph.D. Email: firstname.lastname@example.org