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[ccp4bb] Postdoctoral postion available- Structure-based antimicrobial drug development - UK



Postdoctoral position at the University of Sheffield, UK
PDRA in Structure-based antimicrobial drug development

Applications are invited for a Research Associate in Structural Biology (ideally with some knowledge of in silicon drug screening vHTS) with a start date of 1 Jan 2018 or as soon as possible thereafter. This is initially a 16-month fixed-term position funded by a research contract from DeFENition Ltd, an exciting University of Sheffield spin-out company founded to develop a new generation of anti-bacterial agents capable of targeting antibiotic resistant bacteria. The successful applicant will conduct world-class research in structural biology and will work closely with a second Research Associate tasked with protein manufacture and inhibitor characterization.

The project will be jointly conducted by the Sayers and Baker groups hosted by the Department of Infection, Immunity and Cardiovascular Disease, (IICD) and Department of Molecular Biology & Biotechnology (MBB), respectively at the University of Sheffield, UK.  IICD is situated within the Medical School and encompasses basic research in molecular cell biology in Respiratory Medicine, Infectious Diseases, Renal Medicine, Dermatology, Cardiovascular science and both biomedical and medical imaging. MBB is located centrally in the University campus adjacent to sister departments of Biomedical Science and Animal and Plant Sciences. Together the biology departments host around 100 academic staff and research fellows and teach 1,500 undergraduate students. The three departments are renowned for cutting edge research and have internationally recognized strengths in evolutionary biology and genetics, cell and developmental biology, stem cell biology, behavior and neuroscience, human health and disease, plant science, microbiology, ecology and environmental biology and structural and quantitative biology. Staff also work very closely with scientists and clinicians across the Science, Engineering and Medical Faculties.

Baker and Sayers are members of Sheffield’s Florey Institute for Host Pathogen Interactions http://www.floreyinstitute.com and Sheffield Institute for Nucleic Acids (SInFoNiA) http://genome.sheffield.ac.uk Together we are developing radical solutions to the global problems of disease and antimicrobial drug resistance. Baker and Sayers were part of Unit of Assessment 3, (Allied Health Professions, Dentistry, Nursing and Pharmacy - Biomedical science) which was placed 1st of 96 UK departments in REF2014.

Starting salary £30,688 - £32,548 (plus annual increment).


Please contact me for further information.

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Best wishes
Prof. Jon R Sayers, FRSB
Tel: +44 (0) 114 2159552