We are looking for two postdoctoral fellows to work on methods development for time resolved structural and spectroscopic studies on enzymes using X-rays, especially XFELs. The fellows will work in the Kern/Yachandra/Yano group (http://www2.lbl.gov/vkyachan/ and http://biosciences.lbl.gov/profiles/jan-florian-kern/) at Berkeley Lab’s Molecular Biophysics & Integrated Bioimaging Division. We have been conducting a number of XFEL experiments on several different systems and some recent publications include:
Fuller et al, Nature Methods 2017 http://www.nature.com/nmeth/journal/v14/n4/abs/nmeth.4195.html
Young et al Nature 2016 https://www.nature.com/nature/journal/v540/n7633/full/nature20161.html
Sierra et al Nature Methods 2016 https://www.nature.com/nmeth/journal/v13/n1/full/nmeth.3667.html
Kern et al Nature Communications 2014 https://www.nature.com/articles/ncomms5371
Ideally the candidates should have a good background in one or more of the following fields:
- Macromolecular crystallography
- Microfluidics or stopped-flow instrumentation and application to enzyme studies.
- X-ray spectroscopy of dilute transition metal systems/biological systems.
- Designing of experimental setups for use at synchrotron/X-ray free laser facilities.
- Electrochemistry of redox active enzymes.
Details of the position and instructions how to apply can be found here:
For informal inquiries please feel free to contact me: JFKern@lbl.gov