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[ccp4bb] Postdoc position in ubiquitin signaling
Structural Mechanisms of Ubiquitin Ligases in Cancer
A postdoc position is available in the lab of Sonja Lorenz at the
Rudolf Virchow Center for Experimental Biomedicine, Würzburg, Germany.
The Lorenz lab explores the molecular mechanisms of ubiquitin ligases
and their functions in cancer signaling (ELife 2017;6:e21036). We are
seeking a highly motivated and creative colleague to explore
macromolecular complexes, using cell biological, biochemical, and
structural techniques. Several ambitious projects are available and
can be tailored to individual interests and expertise.
The Rudolf Virchow Center is a highly competitive, international
research institute with outstanding infrastructure. We have access to
state-of-the-art instrumentation in X-ray crystallography, cryo-EM,
high-field NMR and an extensive range of biophysical and cell
biological equipment. We are integrated into a stimulating research
environment that includes the Biocenter, the Research Center for
Infectious Diseases, the University Hospital, and the Max Planck
Research Group in Systems Immunology, and maintain active
international collaborations. Würzburg has strong expertise in
ubiquitin research and was awarded funding for a Research Training
Group “Understanding Ubiquitylation: from molecular mechanisms to
disease” (http://www.uni-wuerzburg.de/grk2243/home/), which the
successful candidate will benefit from.
Applicants should have strong expertise in cell biological techniques
and protein biochemistry. Additional experience with X-ray
crystallography, cryo-EM or interaction proteomics is beneficial.
English language skills are essential; knowledge of German is not
The position can start immediately or upon mutual agreement. Salary
will be according to the German TVL scale. In case of equivalent
qualifications, disabled applicants will be preferentially considered.
Applications should be sent to Sonja Lorenz by email and include a
letter of motivation detailing research interests, expertise, and
career aims; CV; copies of university certificates, and the contact
information of at least two references. Review of applications will
For more information:
Sonja Lorenz, PhD
Rudolf Virchow Center for Experimental Biomedicine, University of