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[ccp4bb] Postdoc position in ubiquitin signaling

Postdoc Position

Structural Mechanisms of Ubiquitin Ligases in Cancer

A postdoc position is available in the lab of Sonja Lorenz at the Rudolf Virchow Center for Experimental Biomedicine, Würzburg, Germany. The Lorenz lab explores the molecular mechanisms of ubiquitin ligases and their functions in cancer signaling (ELife 2017;6:e21036). We are seeking a highly motivated and creative colleague to explore macromolecular complexes, using cell biological, biochemical, and structural techniques. Several ambitious projects are available and can be tailored to individual interests and expertise.

The Rudolf Virchow Center is a highly competitive, international research institute with outstanding infrastructure. We have access to state-of-the-art instrumentation in X-ray crystallography, cryo-EM, high-field NMR and an extensive range of biophysical and cell biological equipment. We are integrated into a stimulating research environment that includes the Biocenter, the Research Center for Infectious Diseases, the University Hospital, and the Max Planck Research Group in Systems Immunology, and maintain active international collaborations. Würzburg has strong expertise in ubiquitin research and was awarded funding for a Research Training Group “Understanding Ubiquitylation: from molecular mechanisms to disease” (http://www.uni-wuerzburg.de/grk2243/home/), which the successful candidate will benefit from.

Applicants should have strong expertise in cell biological techniques and protein biochemistry. Additional experience with X-ray crystallography, cryo-EM or interaction proteomics is beneficial. English language skills are essential; knowledge of German is not required. The position can start immediately or upon mutual agreement. Salary will be according to the German TVL scale. In case of equivalent qualifications, disabled applicants will be preferentially considered.

Applications should be sent to Sonja Lorenz by email and include a letter of motivation detailing research interests, expertise, and career aims; CV; copies of university certificates, and the contact information of at least two references. Review of applications will begin immediately.

For more information:

Sonja Lorenz, PhD
Rudolf Virchow Center for Experimental Biomedicine, University of Würzburg, Germany
E-mail: sonja.lorenz@virchow.uni-wuerzburg.de