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[ccp4bb] Postdoctoral fellow position at Sanofi
Dear CCP4 community,
We are pleased to announce an opening in our Boston area structural biology group for a postdoctoral scholar conducting cryo-electron microscopy and protein crystallography research. A formal job listing is found at https://sanofi.wd3.myworkdayjobs.com/en-US/StudentPrograms/job/Waltham-MA/Postdoctoral-Fellowship--Structural-Biology_R5950-1. Qualified candidates are encouraged to apply. Inquiries including a CV and cover letter may additionally be sent to email@example.com.
A highly motivated and experienced candidate is sought to join the Structural Biology group within Sanofi’s Integrated Drug Discovery Department. The individual will perform structural and functional studies on targets of high priority to our Rare Disease unit. This includes all steps from expression construct design to structure determination of complexes with lead drugs, including data acquisition and analysis. Despite medical significance, published work is often sparse for our rare disease targets. We seek a postdoctoral candidate to address this gap by structurally characterizing such proteins and participating in drug design campaigns using cryo-EM and/or X-ray crystallography. In addition to contributing technical proficiency, the candidate will contribute by staying abreast of literature, implementing new technologies, presenting results in oral and poster formats, and preparing manuscripts for publication.
Our structural biology team works collaboratively in a multidisciplinary department driving toward multiple breakthrough clinical candidates. The post-doc will comprehensively engage in this community as a critical participant in one or more high priority programs. Full infrastructure for protein design and production, plus structural and biophysical characterization, support efficient drug discovery research on-site. Sanofi scientists conduct cryo-EM via a preferred access partnership at a new, fully equipped facility at U. Mass., including Talos Arctica and Titan Krios instruments.
Ph.D. in Structural Biology, Biochemistry, Chemistry, Biophysics, or equivalent, with less than 3 years of postdoctoral experience. Proven in-depth knowledge and expertise in cryo-EM and/or protein crystallography demonstrated preferably through principal authorship in peer-reviewed publication(s). Strong protein chemistry skills with extensive experience in protein purification, cryo-EM grid optimization/protein crystal growth, and experience with data processing and model building.
Strong and concise written and oral communication. Familiarity with lab robotics and automation, as well as protein biophysical or biochemical characterization techniques. Membrane protein research experience is desirable.
Sanofi is a global healthcare leader focused on patients' needs, engaged in the research, development, manufacturing and marketing of therapeutic solutions focused on patients’ needs. Sanofi has core strengths in diabetes solutions, human vaccines, innovative drugs, consumer healthcare, emerging markets and Sanofi Genzyme. At Sanofi, our ambition is to be an integrated global healthcare company, focused on patients’ needs. Much more than just a leading pharmaceutical company, Sanofi is committed to transforming scientific innovations into solutions and services that protect health, enhance life, and respond to the needs of the 7 billion people in the world. We trust our ambition to guide and inspire us as we work to create a future with optimal health and wellness for everyone.