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[ccp4bb] Postdoctoral positions at the NIH in structural and mechanistic studies on integral membrane proteins



Postdoctoral position in small molecule screening and mechanistic studies with membrane proteins at the NIH

 

The research group of Dr. Anirban Banerjee at the National Institute of Health (NIH) is seeking candidates for postdoctoral fellows to start immediately. The broad interests of the lab are in membrane protein structure and function. We are combining structural techniques such as macromolecular crystallography with biophysical and biochemical methods such as reconstitution based functional assays to investigate the structural bases of the mechanisms of integral membrane enzymes and transporters.

 

For this position, we are looking for a candidate who will carry out both structural studies and biochemical experiments on a biomedically important but  functionally understudied integral membrane protein family. Besides understanding the structural and chemical basis of function, one of our long term goals is also to explore using structural information and high throughput assays to discover novel small molecule ligands for this protein in collaboration with other labs at the NIH 

 

The DC Metro area is a wonderful place to live, the weather is pleasant and the NIH is a vibrant international community. In terms of scientific opportunities, the NIH is absolutely unique in bringing scientists from virtually all areas of biomedical sciences in one campus. Our lab is part of the Cell Biology and Neurobiology Branch in the National Institute of Child Health and Human Development (NICHD). Our lab also has an affiliation to the National Institute of Neurological Disorders and Stroke (NINDS). We interact with several other labs at the NIH who are interested in structural biology and membrane proteins.

 

Qualifications

The candidates should hold a Ph. D. degree, be author of at least one first author publication and have a strong background in biochemistry or structural biology. Experience with basic molecular biology, protein _expression_, purification and biochemical characterization are required. Prior experience in membrane protein biochemistry or insect/mammalian _expression_ systems will be added advantages.

Interested candidates can send an email of interest to anirban.banerjee@nih.gov with a CV and a summary of previous research experience and interests.