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[ccp4bb] Postdoc (Structural Cell Biology) on targeting E3 ubiquitin ligases at Dundee

Job title: Postdoctoral Research Assistant (E3 ubiquitin ligases)
Job location: DundeeUK
Job closes: 21-May-2017

Professor Alessio Ciulli’s laboratory is seeking a postdoctoral researcher to undertake research in collaboration with one of the leading pharmaceutical companies supporting the Division of Signal Transduction Therapy (DSTT). The DSTT facilitates collaborations between some of the world’s major pharmaceutical companies (Boehringer Ingelheim, GlaxoSmithKline, and Merck-Serono) and leading Dundee-based researchers with a proven track record of achievement in understanding and exploiting the fundamental molecular causes of human disease in the fields of cancer, immune-regulation, neurodegeneration and hypertension resulting from disruptions in protein ubiquitylation, phosphorylation and other signalling networks.

The successful applicant will be based within the Ciulli lab in Dundee. The laboratory is pioneering novel chemical structural biology approaches to target E3 ligases (see Lucas and Ciulli, Curr. Opin Struct Biol 2017 and Gadd et al. Nat. Chem Biol. 2017 for recent publications from the group in this area). The successful applicant is expected to employ state-of-the-art structural biology, cell biology and biophysical approaches to conduct molecular and structural studies on disease-relevant human E3 ubiquitin ligases. 

The post is available immediately and salary will depend on experience, but will be up to £38,183. 
This is a unique opportunity to gain experience in industry-style drug discovery within an academic setting.

The position is available for 2 years with possibility of further 2 years extension.

Further details about the position and how to apply please visit

Alessio Ciulli, FRSC
Professor of Chemical & Structural Biology
School of Life Sciences, University of Dundee
Division of Biological Chemistry and Drug Discovery
James Black Centre, Dow Street, Dundee DD1 5EH
United Kingdom

Phone: +44 (0)1382 386230    Fax: +44 (0)1382 386373