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[ccp4bb] Ph.D studentship in Structural Biology in Oxford



A 4-year Ph.D studentship in Structural Biology starting October 2014 is available in the Research Group led by Dr. Christian Siebold. Our group, based in the Division of Structural Biology (STRUBI) at the Wellcome Trust Centre for Human Genetics, University of Oxford is primarily focused on the structural biology of extracellular recognition and signalling complexes in development and cancer (https://www.strubi.ox.ac.uk/research/christian-siebold). 

STRUBI harbours a well-developed infrastructure for large-scale soluble and membrane protein production, purification and crystallization with excellent access to the DIAMOND synchrotron and a range of biophysical and cell-based facilities.

The doctoral project concerns the structural and functional characterization of the Hedgehog and Bone Morphogenetic Protein signalling pathways. More details can be found under:

http://www.ndm.ox.ac.uk/doctoral-projects/project/structural-biology-of-cell-surface-morphogen-signalling

The studentship is funded by Cancer Research UK. Applicants should hold or expect to gain a first or upper second class honours degree. Cancer Research UK will pay a competitive stipend (£19.000 p.a.) as well as University and College fees. Ideal candidates have a strong background in biochemistry and molecular or cell biology, but science graduates in general are welcome to apply. It would be an advantage, but is not necessary, for the candidate to have laboratory experience in any of the following: cloning, mutagenesis, protein expression, purification and crystallographic techniques. Candidates whose first language is not English will be asked to submit a certificate of proficiency in the English language (e.g. IELTS 7.5). 

Applications should be submitted via the Nuffield Department of Medicine (NDM) Prize Studentship application pipeline (http://www.ndm.ox.ac.uk/for-applicants), quoting project number 118 and “Cancer Research UK” as funding source. The closing date for applications is 10 January 2014. Interviews are expected to take place on 29 and 30 January 2014.

For further information please contact Christian Siebold (christian@strubi.ox.ac.uk).