Postdoctoral Research Position in Structural Biology of Phosphoinositide Signaling
The mechanistic Target of Rapamycin (mTOR) is involved in sensing amino-acid availability, oxygen, ATP levels and growth-factor signalling. Its activity coordinates mRNA translation, lipid metabolism, mitochondrial functions, ribosome biogenesis and autophagy. The Ragulator and Rhebulator complexes control mTORC1 through two types of small GTPases, the Rags and Rheb. The three-year Cancer Research UK funded position focuses on the structural biology of mTORC1 assembled with its regulators on lysosomal membranes.
The research group of Roger Williams in the MRC
Laboratory of Molecular Biology has an opening for a Postdoctoral
Scientist to carry out structural and functional studies of
mTOR-containing complexes. The programme involves cryo-electron
microscopy, X-ray crystallography, H/D exchange mass spectrometry, as
well as other biophysical and biochemical approaches.
The successful applicant will be awarded a 3 year Career Development Fellowship/MRC Postdoctoral Training Scheme. The fellowship is a training and development position for a Postdoctoral Scientist who has recently completed their doctoral studies, or is moving into a new research discipline.
Working for the MRC provides a whole host of benefits including a final salary pension scheme, Benenden Healthcare membership and excellent holiday entitlement. You will also have access to employee shopping/travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers.
The MRC Laboratory of Molecular Biology is one of the birthplaces of molecular biology and is an internationally renowned centre for fundamental biomedical research. The LMB has an excellent record of innovative basic research leading to applications in medicine. Scientists are drawn to the LMB from all over the world, thus creating a lively and international community for the exchange of ideas and technical innovation.
To apply and access full details of the vacancy please visit our job board at https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/573. If you are unable to apply online please contact us at firstname.lastname@example.org .
Closing date: 7th May 2017
Final appointments will be subject to a pre-employment screening.
MRC Laboratory of Molecular Biology
Francis Crick Avenue
Cambridge Biomedical Campus
Cambridge CB2 0QH, UK
Phone lab: +44 1223 267094