Job-posting - Seeking structural biologist with cryo-EM expertise at GSK
A vacancy for a structural biologist with cryo-EM expertise has opened up within the UK structural and biophysical sciences group at GlaxoSmithKline R&D. Joining
an experienced multi-disciplinary group, this is an exciting opportunity for a motivated individual to complement and help shape our current capabilities in the EM area.
This is a permanent, full-time position suitable for a PhD degree holder (or equivalent).
To apply for this role and for further details, please click on the link below (Vacancy no : WD106591)
A full job description is also included at the end of this message.
Applications for this vacancy are to be made online by 24th MARCH
Informal inquiries can be sent to firstname.lastname@example.org
Thank you for your interest,
UK Head Structural & Biophysics Sciences
Tel no: +44 1438 763342
Full Job Description (WD78277):
GlaxoSmithKline is a world leading research-based pharmaceutical company. We are focused around three core businesses: Pharmaceuticals,
Vaccines and GSK Consumer Healthcare. We have a significant global presence with commercial operations in more than 150 countries, a network of 84 manufacturing sites in 36 countries and large R&D centres in the UK, US, Belgium and China.
The UK Structural and Biophysical Sciences group is a multi-disciplinary department within GSK R&D that provides molecular insights into drug discovery for both small molecule and biopharmaceutical programs.
We currently have an exciting opportunity for a laboratory-based scientist with expertise in state-of-the-art electron microscopy techniques to play an influential and key role in the application and development of these methods across
small molecule and therapeutic protein programs. This individual will have extensive experience in the sample preparation and optimisation processes necessary to produce high-quality molecular images of protein structure, including direct experience of Cryo-EM
methodologies. Experience of data analysis and interpretation is also expected. Being responsible for delivering structural insights to support program teams and contributing to the wider protein structural and biophysical area by identifying and driving
forward improvements and innovations that advance drug discovery projects, the individual must be a collaborative team player able to work successfully with other scientists within the department and within diverse teams.
Key Responsibilities and Accountabilities:
• Design and perform technical experiments in the EM area (sample preparation, optimisation and analysis).
• Document and communicate scientific results clearly and promptly.
• Provide strong scientific lead to shape EM strategy within structural biology and across therapeutic discovery programs.
• Build EM capabilities and infrastructure through interactions with the internal and external scientific community.
• Maintain scientific excellence and lead in a rapidly evolving area e.g. through interactions such as the FEI/LMB/Pharm consortium.
• Become an integral team member of multiple project teams.
Key Capabilities and Proficiency:
1. Technical expertise leading to Impact
Evidence of specific and in depth knowledge of transmission electron microscopy used as a structural technique, especially single particle cryo-EM. A track record of its application to address scientific problems relevant to pharmaceutical
2. Influence and Scientific awareness
Evidence of engagement with external scientific environment including the ability to identify and pursue opportunities that advance capabilities within own research area.
3. Team work
Demonstrable ability to both directly and indirectly influence and impact the progression of programs of research and to work in multi-disciplinary teams, displaying appropriate interpersonal skills and team work