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[ccp4bb] PhD position AND postdoc position available

Dear colleagues,

We invite applications for a PhD position and a postdoc position in the research group of Dr. Sonja Lorenz at the Rudolf Virchow Center for Experimental Biomedicine, Würzburg, Germany.

The Lorenz lab explores the catalytic and regulatory mechanisms of ubiquitin ligases and their functions in cancer signalling (see eLife 2017;6:e21036). We combine X-ray crystallography with biophysical, biochemical, and cell biological analyses. Depending on individual qualifications and interests, the successful applicants will have the opportunity to gain experience in various aspects of this multidisciplinary approach.

The Rudolf Virchow Center is a highly competitive international research institute with outstanding technical infrastructure. The Lorenz lab has access to state-of-the-art instrumentation in X-ray crystallography, high-field NMR, cryo-EM, and an extensive range of modern biophysical and cell biological equipment. We are integrated into a stimulating research environment that includes the Biocenter, the Research Center for Infectious Diseases, and the university hospital in Würzburg, and we maintain several active international collaborations.

PhD applicants should have a M.Sc. degree in molecular biology, biochemistry or a related discipline and a strong interest in enzymatic mechanisms and structure-function studies on proteins. Experience in protein biochemistry is desirable. Postdoc applicants should have strong expertise in protein X-ray crystallography, protein biochemistry, and biophysics. Experience with mammalian or baculovirus expression systems is beneficial.
English language skills are essential; knowledge of German is not required.

The successful PhD applicant will have the opportunity to enroll in the ‘Graduate School of Life Sciences’ in Würzburg – a prestigious international PhD program funded by the German Excellence Initiative. He/she will also be affiliated with the new DFG-funded Graduate Training Group “Understanding Ubiquitylation: from molecular mechanisms to disease” (http://www.uni-wuerzburg.de/grk2243/home/).

Both positions can start immediately or upon mutual agreement. Salary will be according to the German TVL scale. In case of equivalent qualifications, disabled applicants will be preferentially considered. Würzburg is located in a beautiful, wine-growing area in proximity to Frankfurt (1 hour by train) and Munich (2 hours by train).

Applications should be sent to Sonja Lorenz by email (sonja.lorenz@virchow.uni-wuerzburg.de) and are expected to include a letter of motivation detailing research interests and expertise, a CV, and the contact information for at least two references. Review of applications will begin immediately.

Lab homepages:


Sonja Lorenz, PhD
Rudolf Virchow Center for Experimental Biomedicine
Josef-Schneider-Strasse 2, Haus D15
97080 Würzburg, Germany