The position will be based in the University of Cambridge, Department of Biochemistry, Tennis Court Road, Central Cambridge. The project focuses on the mechanisms by which regulatory RNA binding proteins control splicing complex assembly at regulated splice sites, and builds upon our recent discovery of a master splicing regulator that acts in smooth muscle cells. It will involve a range of biochemical, molecular, proteomic, biophysical, structural and single-molecule techniques based in the PI's and collaborators labs. We need to recruit someone with expertise in structural biology (X-ray crystallography, Cryo-EM) and associated biophysical techniques to complement our established expertise in RNA molecular biology. Prior knowledge or experience of RNA splicing, RNA biology or nucleic acid-protein assemblies would be an advantage. The funds for this post are available for 5 years in the first instance.
Further details available at: http://www.jobs.cam.ac.uk/job/17208/.