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[ccp4bb] NIH-funded postdoc position

Dear colleagues,

Please see below an ad for an NIH-funded postdoc position in my laboratory.

Thank you,

at Brown University, Providence, Rhode Island, USA

The Deaconescu Lab at Brown University is seeking a motivated and energetic postdoctoral research to join our work on a NIH-funded project.

Our work focuses on stress responses such as to DNA damage and starvation, and particularly on the interplay between transcription, DNA repair and chromatin remodeling. Our work so far has  elucidated the function and mechanochemistry of DNA-based motors and also of cytoskeletal regulators using a combination of biochemical, biophysical and structural techniques. (e.g. X-ray crystallography, small-angle X-ray scattering, transmission electron microscopy). For recent examples of work, please see Deaconescu and Suhanovsky, Photochem and Photobiology (2016), Kutter et al. JMB (2016), Szyk et al., Cell (2014), Deaconescu et al., PNAS (2012), Szyk et al., NSMB (2012) and Deaconescu et al., TIBS (2013).

Brown University has a Structural Biology Core Facility managed by a PhD-level scientist and features, among others, an X-ray generator equipped with an ACTOR mounting robot as well as 500 and 850 MHz NMR magnets.

A successful candidate should have the following qualifications: a Ph.D. in the field of Molecular Biology, Cell Biology, Biochemistry or related field; an established track-record of publications in peer-reviewed journals; solid experience in the biochemistry of complex DNA-binding proteins, their purification from E.coli/yeast _expression_ systems as well as their characterization using functional studies such as by isothermal titration calorimetry, transcription assays, circular dichroism and fluorescence.  Prior knowledge of crystallography would be a plus, but is not required. Must be highly motivated and work independently as well as in a team. Excellent spoken and written English are required. New Ph.D. graduates are encouraged to apply. Salary and starting date are negotiable.

Interested candidates should send a CV, one page research experience summary and contact information for three references to alexandra_deaconescu[at]brown.edu. Salary and starting date are negotiable.   Please write Postdoctoral Candidate in the e-mail subject header.   Brown University, an Ivy League institution, is located less than one hour away by train from Boston.  

Lab webpage: https://deaconesculab.com

Alexandra M. Deaconescu, B.E., Ph.D.
Assistant Professor of Molecular Biology, Cell Biology and Biochemistry
Brown University

For mail:
70 Ship St. G-E4
Providence, RI 02903

For courier (FEDEX):
70 Ship St.
Chestnut St. Loading Dock
Providence, RI 02903

Phone: 401-863-3215
Lab website: http://deaconesculab.com

Administrative Assistant: Mr. Ray Windsor (phone: 401-863-7446)