The Elmlund laboratory (http://simplecryoem.com
), Monash University, Melbourne, develops methods for single particle electron microscopy and conducts an integrative structural biology research program, focussing on two master regulators of Eukaryotic transcription: TFIID and SAGA. Our biological aims are to understand how the mechanisms for transcription initiation and start-site selection differ between constitutively transcribed (housekeeping) and stress-inducible genes by studying the large but transient protein-protein and protein-DNA complexes involved using a combination of techniques, including cryo-EM, mass-spectrometry and biochemical assays. We have three positions available:
(1) Postdoctoral fellow (molecular basis of stress-inducible gene regulation)
(2) Postdoctoral fellow (transcription coupled chromatin remodeling)
(3) Scientific programmer (image processing for single-particle cryo-EM)
Monash University is a leading research university in Australia that received a rank of 67 worldwide in the 2015/16 report from QS world university rankings. State-of-the-art technology is available to the Project via Monash’s research platform strategy, with The Clive and Vera Ramaciotti Centre for Structural Cryo-EM housing a Titan KRIOS with K2 detector, energy filter and Volta phase plate. Extensive computational infrastructure is available to the project via the MASSIVE3 supercomputer (https://www.massive.org.au/
). The excellent structural biology community surrounding the facility, the nearby Australian Synchrotron and other major research programs, such as the ARC Centre of Excellence in Advanced Molecular Imaging (led from Monash), provides a unique opportunity to execute the projects.
We would appreciate if you could share this announcement with suitably skilled and interested scientists in your network.
Dominika & Hans Elmlund