Sanofi Genzyme focuses on developing specialty treatments for debilitating diseases that are often difficult to diagnose and treat, providing hope to patients and their families.
Genzyme Corporation (a Sanofi company) and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or _expression_; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
A highly motivated candidate is sought to join the Protein Engineering group within the Biologic Research Department. The individual will carry out purification and crystallization of biologics targets, especially antibody-antigen complexes; determining the structures of protein-ligands; analyzing and interpreting the structures; presenting and communicating the results to other science teams. A successful candidate will perform complex analytical procedures, and also contribute to the overall project design and implementation of new technology.
Ph.D. in protein crystallography or equivalent with less than 5 years of postdoctoral experience. Proven in-depth knowledge and expertise in protein structural biology demonstrated preferably through principal authorship in peer-reviewed publication(s). Specifically, candidates must have extensive experience in protein construct optimization, protein purification, crystallization, data collection and structure determination with strong protein chemistry skills. Expertise in common crystallographic software such as CCP4, HKL, Phenix is required.
Strong and consistent written and oral communication ability. Familiarity with lab robotics and automation and other protein biophysical characterization techniques is preferred. Knowledge of antibody structures and experience with electron microscopy is also desirable.