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[ccp4bb] PhD position available

Posted on behalf of Prof. Stefan Knapp


The Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Germany, currently offers a position for a PhD student (E13 TV-G-U, 65%) in the research group of Prof Knapp (http://www.uni-frankfurt.de/53483664/Knapp). The position is available immediately and the appointment is funded for 3 years with the possibility for extension. Female candidates are especially encouraged to apply. Precedence will be given to handicapped candidates at equal qualification.


The project is a collaboration with the group of Prof. Martin Zörnig (Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy) and other international and local research groups that aim to develop new therapies for the treatment of hepatocellular carcinoma by targeting the FUSE Binding Protein 1 (FUBP1), a pro-proliferative and anti-apoptotic oncoprotein. The work of the PhD project comprises structural studies on FUBP1 using X-ray crystallography and other biophysical methods as well as ligand binding studies of FUBP1 inhibitors that we would like to develop into drug candidates.

The ideal candidate would have a Master degree in Chemistry, Biochemistry or Biophysics and experience in protein biochemistry and protein _expression_. We are an international research group and good knowledge of English as well as excellent communication skills will be essential.


The planned research will be done in a highly stimulating and international research environment, integrated in the life science campus Riedberg in collaboration with the Institute for Tumor Biology and Experimental Therapy. Interested candidates are encouraged to submit their CVs to the following e-mail address: knapp@pharmchem.uni-frankfurt.de


Closing date for the application is 31st October 2016.



Prof. Stefan Knapp