Subject:
Postdoctoral
Fellowship at Scripps Florida in Crystallography
Postdoctoral Research
Associate positions are immediately available for structure-function studies of
cytoskeletal proteins that control signaling downstream of adherens junctions
and focal adhesions. Fellows will join an exciting research environment of the
Izard laboratory in new state-of-the-art facilities of the Scripps Florida
campus of The Scripps Research Institute (TSRI), which is renowned in the
Structural Biology field. The Izard laboratory has made many contributions in
the cytoskeleton field (http://www.scripps.edu/florida/cancerbio/izard).
The position provides an outstanding training
program in protein biochemistry and structure, and also in molecular and
cellular biology, in a highly dynamic and team-oriented research program.
Successful candidates will work in a cutting-edge
research environment that tackles this important new arena in cancer and cell
biology. The laboratory has outstanding facilities for cell biology, molecular
biology, protein _expression_, purification, and biochemistry, and protein
crystallography.
Scripps Florida provides an incredibly rich
scientific environment. Notably, TSRI faculty include an outstanding cadre of
senior colleagues, including three Nobel Laureates and about twenty Members of
The National Academy of Sciences, including several in crystallography and
biophysics. In 2008, Scripps Florida moved into three new, state-of-the-art
research buildings and will expand to eventually house 80 faculty-level
investigators. Scripps Florida has a large cast of outstanding Cores
that facilitate basic research and drug development. The
unique infrastructure at Scripps Florida includes the application of unique
chemical, genomic, proteomic, informatics, and high-throughput screening and
engineering tools for the discovery of novel biomolecules.
Scripps Florida is a new member of the South East
Regional Collaborative Access Team (SER-CAT) that constructed two beam lines at
the Advanced Photon Source (APS) at Argonne National Laboratory. The insertion
device and bending magnet beam lines are available for all the synchrotron-related
data collection needs for the post-doctoral fellows.
Scripps Florida provides a HighFlux X-ray diffraction system, specifically a
Rigaku MicroMax-007 HF, a second-generation true microfocus rotating anode
generator. Scripps Florida also provides an Osmic VariMax optics system and the
Proteros Free Mounting System to control the humidity and to optimize
diffraction characteristics, including resolution, mosaicity, and anisotropy,
as well as reduced X-ray background. Finally, the X-ray laboratory houses the
mar345 Image Plate detector.
Palm Beach County is one of the most sought-after communities in the country
and offers residents an incomparable lifestyle in a family-friendly community
with public playgrounds and parks and access to world-class shopping and
unmatched outdoor recreation. It is one of the safest communities in the United
States with virtually no crime. The Atlantic Ocean with its 45 miles of
spectacular beaches and signature Coconut Palms provides an exclusive getaway
in a warm, sunny climate throughout most of the year. There are a number of
exquisite art galleries as well as arts and crafts festivals. This
golfer’s paradise is also home of the Professional Golfers Association of
America (PGA).
Applicants must have a Ph.D. degree and experience in protein crystallography. Please send CV, a summary of research experience and
interests, and names, addresses, e-mail and telephone numbers of 3 references
to:
Dr. T. Izard (mkernick@scripps.edu)
Associate Professor with Tenure
Director, Macromolecular Crystallography Scripps-Florida
Cell Adhesion Laboratory
Department of Cancer Biology
The Scripps Research Institute
Jupiter, FL 33458