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[ccp4bb] Postdoc position to investigate the structural mechanisms of ubiquitin ligases

Postdoc Position

Structural Mechanisms of Ubiquitin Ligases in Cancer

We are seeking to appoint a highly motivated postdoctoral researcher in the group of Dr. Sonja Lorenz at the Rudolf Virchow Center for Experimental Biomedicine in Würzburg, Germany, to investigate the structural mechanisms of ubiquitin ligases. Several ambitious projects are available and can be tailored to individual interests and expertise.

The Lorenz lab is supported by the Emmy Noether Program of the German Research Foundation (DFG) and explores the molecular mechanisms of ubiquitin signaling. We aim to uncover the catalytic and regulatory mechanisms of ubiquitination enzymes and their functions in cancer signaling. Our lab combines structural biology (X-ray crystallography, NMR spectroscopy) with biophysical and cell biological analyses.

The Rudolf Virchow Center is a highly competitive international research institute with an outstanding technical infrastructure. The Lorenz lab has access to state-of-the-art instrumentation in X-ray crystallography, high-field NMR, cryo-EM, and an extensive range of modern biophysical and cell biological equipment. We are integrated into a stimulating research environment that includes the Biocenter, the Research Center for Infectious Diseases, and the university hospital in Würzburg, and we maintain several active international collaborations.

Applicants should have a PhD in the life sciences and a strong background in X-ray crystallography. Additional experience with the Baculovirus or mammalian expression systems and/or cryo-EM would be beneficial. Good English language skills are essential; knowledge of German is not required.

The position can start immediately or upon mutual agreement. Salary is based on the German TVL scale. In case of equivalent qualifications, disabled applicants will be preferentially considered. Applications and queries about the lab can be sent to Sonja Lorenz by email (sonja.lorenz@virchow.uni-wuerzburg.de). Applications should include a letter of motivation stating research interests and expertise, a CV, and the contact information of at least two references. Review of applications will begin immediately.

Lab homepages:



Sonja Lorenz, PhD
Rudolf Virchow Center for Experimental Biomedicine
University of Würzburg
Josef-Schneider-Strasse 2, Haus D15
97080 Würzburg

Attachment: Postdoc_Lorenz.pdf
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