Collaborative Computational Project No. 4
Software for Macromolecular X-Ray Crystallography

CCP4 exists to produce and support a world-leading, integrated suite of programs that allows researchers to determine macromolecular structures by X-ray crystallography, and other biophysical techniques. CCP4 aims to develop and support the development of cutting edge approaches to experimental determination and analysis of protein structure, and integrate these approaches into the suite. CCP4 is a community based resource that supports the widest possible researcher community, embracing academic, not for profit, and for profit research. CCP4 aims to play a key role in the education and training of scientists in experimental structural biology. It encourages the wide dissemination of new ideas, techniques and practice.

CCP4 is supported by
CCP4 is a participant of
CCP4 Software Suite
CCP4 special issue The current version is CCP4 6.4.0 (11 October 2013). The new and updated packages include:
  • ARP/wARP integrated download and installation for ARP license holders
  • refmac5.7 improved jelly body refinement refinement and use of restraint information
  • phaser 2.5.1 for MR and EP, better handling of tNCS
  • aimless for scaling and merging
  • prosmart for alignment of protein changes and refmac external restraints
  • nautilus for automatic building of RNA/DNA
See here for details of new features and updates. For the latest patches and updates to the current release of CCP4 see the Updates page.
CCP4 Study Weekend 2015
See details of past Study Weekends and proceedings
CCP4 Online Automated Webservices
BALBES NEW! The CCP4-online webserver is now available. Users can make use of BALBES and MrBUMP, the automated molecular replacement services. Zanuda, the refinement result checking software and PISA for the calculation and analysis of macromolecular surfaces and interfaces are also available. To access the services please click here.
CCP4 Documentation Wiki
CCP4 Wiki For up-to-date documentation on all of CCP4's software and lots of other useful information for X-ray crystallographers see the CCP4 Wiki.
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