Collaborative Computational Project No. 4
Software for Macromolecular X-Ray Crystallography


The AMPLE project - a joint development by CCP4 and the University of Liverpool


Ample was first released with CCP4 6.3.0.


Jaclyn Bibby, Ronan M. Keegan, Olga Mayans, Martyn D. Winn and Daniel J. Rigden (2012) "AMPLE: a cluster-and-truncate approach to solve the crystal structures of small proteins using rapidly computed ab initio models" Acta Cryst. D68, 1622-1631
J. Bibby, R. M. Keegan, O. Mayans, M. D. Winn and D. J. Rigden (2013) "Application of the AMPLE cluster-and-truncate approach to NMR structures for molecular replacement" Acta Cryst. D69, 2194-2201


The development of Ample has been funded by the BBSRC and EPSRC under grant BB/H013652/1 "Ab initio protein modelling for automated X-ray crystal structure solution"